Assistant Professor Chester Drum
MD (USA), PhD (USA)
Consultant, Department of Cardiology, NUHCS
Assistant Professor, Department of Medicine, Yong Loo Lin School of Medicine, NUS
Assistant Professor Chester Drum is a certified consultant cardiologist and internal medicine physician practicing at the National University Hospital in Singapore and an assistant professor at the Yong Loo Lin School of Medicine, National University of Singapore.
Asst. Prof. Drum’s research interests centre on regulatory science and advanced materials engineering. With funding from the Strategic Positioning Fund of the Biomedical Research Council, A*STAR, Asst. Prof. Drum’s lab develops advanced models of patient specific drug effects by combining electronic medical records with quantified estimations of pharmacokinetic variability in real world patient cohorts. Through technique development in quantitative mass spectrometry, protein engineering and Baysian population modelling, Asst. Prof. Drum seeks to create technologies that enable cost effective surveillance of medical treatments in the post-market setting.
The ultimate goal of Asst. Prof. Drum’s research efforts is to provide real time readouts for patients to understand the risk benefit of commonly prescribed medications throughout the lifecycle of a drug. Asst. Prof. Drum’s lab is founded on the belief that patient access to medical information is a societal obligation and requires technical enablers not currently available in the marketplace.
The material engineering part of Asst. Prof Drum’s laboratory is currently funded by the Singapore MIT Alliance for Research and Technology (SMART) and develops advanced biomaterials which respond to their environment. Examples include industrially scalable incubators which accelerate production of biological therapeutics and chemistry based systems for light responsive biomaterials.
Asst Prof. Drum received an undergraduate degree with honors from the University of Chicago in philosophy and went on to obtain an M.D. and Ph.D., receiving the prestigious Harold Lamport Award for top dissertation in the Biological Sciences. He was trained in medicine at the University of California, San Diego and as a cardiologist at Brigham and Women’s Hospital in Boston, Massachusetts. He has published in top tier journals, including Nature, and received multiple awards including the Burroughs Wellcome Career Award for Medical Scientists and the Clinician Scientist Award from the NMRC, Singapore.
- Real-time measurement of thrombin generation using continuous droplet microfluidics. Yu J, Tao D, Ng EX, Drum CL, Liu AQ, Chen CH. Biomicrofluidics. 2014 Sep 3;8(5):052108.
- Adaptive licensing: taking the next step in the evolution of drug approval. Eichler HG, Oye K, Baird LG, Abadie E, Brown J, Drum CL, Ferguson J, Garner S, Honig P, Hukkelhoven M, Lim JC, Lim R, Lumpkin MM, Neil G, O'Rourke B, Pezalla E, Shoda D, Seyfert-Margolis V, Sigal EV, Sobotka J, Tan D, Unger TF, Hirsch G. Clin Pharmacol Ther. 2012 Mar;91(3):426-37.
- Superstructure based on β-CD self-assembly induced by a small guest molecule. De Sousa FB, Lima AC, Denadai AM, Anconi CP, De Almeida WB, Novato WT, Dos Santos HF, Drum CL, Langer R, Sinisterra RD. Phys Chem Chem Phys. 2012 Feb 14;14(6):1934-44.
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